AXL (Gas6 Dependent)/BaF3
CBP73249
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| I. Introduction | |
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Cell Line Name： |
AXL (Gas6 Dependent)/BaF3 |
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Host Cell: |
BA/F3 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
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Freeze Medium: |
90% FBS+10% DMSO |
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Complete Culture Medium: |
RPMI-1640+10%FBS+1ug/ml Human Gas6 |
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Mycoplasma Status: |
Negative |
| II. Background | |
| AXL (TYRO7) is a receptor tyrosine kinase that is overexpressed in various forms of cancer, including breast, prostate, colorectal, and non-small cell cancers. AXL overexpression has been shown to encourage tumor progression and metastasis and to decrease the anti-tumor immune response, making AXL an attractive candidate for anticancer therapies. | |
| III. Representative Data | |
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1. Anti-proliferation assay
Figure . Anti-proliferation assay of three reference compounds on the AXL (Gas6 Dependent)/BaF3 Stable Cell Line. |
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